What can biofabrication do for space and what can space do for biofabrication?

Biofabrication in space explores the production of biological materials, such as tissues and organoids, using microgravity to overcome limitations faced on Earth. The unique environment of space enables more precise cell growth and scaffold-free tissue engineering, advancing regenerative medicine, drug testing, and future deep-space exploration.

“Under microgravity, it is possible to engineer constructs using more fluidic channels and thus more biocompatible bioinks. Microgravity enables biofabrication of tissue and organ constructs of more complex geometries, thus facilitating novel scaffold-, label-, and nozzle-free technologies based on multi-levitation principles. However, when exposed to microgravity and cosmic radiation, biofabricated tissues could be used to study pathophysiological phenomena that will be useful on Earth and for deep space manned missions. Here, we provide leading concepts about the potential mutual benefits of the application of biofabrication technologies in space.”

Honoured to be listed among those giants authoring this review published in Trends in Biotechnology, together with L. Moroni, K. Tabury, D. Grimm & V. Mironov. Check out the links below to read the full paper.

Follow us on social media to learn more about other relevant projects on related topics, such as AstroCardia, PULSE and M4PM (Microgravity for Personalised Medicine).